Zika virus literature review

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There are no licensed medical countermeasures vaccines, therapies or preventive drugs available for Zika virus infection and disease. This paper reviews the status of the Zika virus outbreak, including medical countermeasure options, with a focus on how the epidemiology, insect vectors, neuropathology, virology and immunology inform options and strategies available for medical countermeasure development and deployment. Multiple information sources were employed to support the review. These included publically available literature, patents, official communications, English and Lusophone lay press. Online surveys were distributed to physicians in the US, Mexico and Argentina and responses analyzed. Computational epitope analysis as well as infectious disease outbreak modeling and forecasting were implemented.

The emergence of zika virus a narrative review

Factsheet about Zika virus disease

The NIH Library physical space is currently closed. Library staff are still ready to assist you with your information needs. See our online services, training, and resources, or ask us a question. Aedes aegypti, the primary vector of various arthropod-borne viral arboviral diseases such as dengue and Zika, is a popular laboratory model in vector biology.

Zika Virus: A Review of Literature

Anna R. Plourde, Evan M. Zika virus is a mosquitoborne flavivirus that is the focus of an ongoing pandemic and public health emergency.
Metrics details. ZIKV is one of the rising pathogens promptly surpassing geographical borders. ZIKV infection was characterized by mild disease with fever, headache, rash, arthralgia and conjunctivitis, with exceptional reports of an association with Guillain—Barre syndrome GBS and microcephaly. However, since the end of , an increase in the number of GBS associated cases and an astonishing number of microcephaly in fetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns.

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